As part of the PROMIZING study, staff at the University Hospital of Heraklion follow patients during their weaning period. The 840 ventilator allows the continuous recording of all the numerical values that appear on the ventilator screen. Therefore, the PROMIZING study enables the collection of a large dataset with information on the breathing patterns of patients during the weaning period. The only equipment necessary to obtain these recordings are a PC and a connecting cable. Collection of this data will allow for:

  • Input for occasional missing values on the study logs
  • Confirmation of protocol adherence
  • Monitoring of ventilator setup changes during weaning in more detail
  • Evaluation of breathing patterns during weaning
  • Evaluation of driving pressure during weaning in patients ventilated in PAV mode.

Driving pressure during proportional assist ventilation: an observational study

In a recent study, the driving pressure during assisted ventilation was analyzed using these recordings.

Vaporidi et al. Ann. Intensive Care (2019) 9:1. https://doi.org/10.1186/s13613-018-0477-4

As part of this study, a program was developed to analyze the data from the ventilator, including artifact rejection, smoothing, computation of driving pressure, etc. The ventilator data is anonymized onsite by the investigator who makes the recording by entering an anonymous file name.
The PROMIZING study represents a unique opportunity to obtain data on the breathing patterns of critically ill patients during the weaning process, and, importantly, from multiple centers using a detailed ventilation protocol. This data can help us identify and better characterize:

  • the breathing patterns of patients during weaning
  • potential differences in breathing patterns between PAV+ and PS
  • patterns associated with weaning failure
  • the incidence of high driving pressure during assisted ventilation
  • risk factors for high driving pressure
Slideshow: Instructions_for_data_acquisition_840-002Download

Continuous recording of ventilator data for the PROMIZING study

As part of the PROMIZING study we follow patients during the weaning period.

The 840 ventilator allows the continuous recording of all the numerical values that appear on the ventilator screen.  Therefore, the PROMIZING study enables us to collect a large dataset with information on the breathing patterns of patients during the weaning period.

The equipment necessary to obtain the recording is just a PC and a connecting cable. Detailed instructions on how to make the connections and how to obtain the recordings will be provided on the website.

The data to be collected include:

  • Date/time
  • Ventilator settings
  • Respiratory parameters measured by the ventilator, such as peak and mean pressure, tidal volume and minute ventilation, respiratory rate and Ti, and, in PAV mode, resistance and compliance.
  • Waveforms are not recorded with this protocol, only numerical data as seen on the ventilator screen.
  • A template of the excel file of the parameters collected by the ventilator can be found as attachment.

These data will allow:

  • Input for occasional missing values on the study logs
  • Confirmation of protocol adherence
  • Monitor of ventilator setup changes during weaning in more detail
  • Evaluation of breathing patterns during weaning
  • Evaluation of driving pressure during weaning in patients ventilated in PAV mode.

In a recent study the driving pressure during assisted ventilation was analyzed using this type of recording (Vaporidi et al. Annals of Intensive Care, Jan. 2019). As part of this study we have developed the program to analyze the data from the ventilator, which includes artifact rejection, smoothing, computation of driving pressure etc.  The ventilator data are anonymized onsite, by the investigator who makes the recording as the filename is selected.

The PROMIZING study represents a unique opportunity to obtain data on the breathing patterns of critically ill patients during the weaning process, and, importantly, from multiple centers using a detailed ventilation protocol.